"Man Up" is about three men who try to reignite the tough guy in them and what it takes to be the "real man" as Will (Mather Zickel), who is married to Theresa (Teri Polo), wants to find out what it takes to bring out the "real man" inside. Being a man in these times has changed and Will is focused only on getting his son Nathan (Jake Johnson) the perfect gift for his 13th birthday. While Craig (Christopher Moynihan) still has feelings for his college ex-girlfriend Lisa, Kenny (Dan Fogler) suppresses his anger towards his ex-wife Brenda (Amanda Detmer) by saying, "What would Tobey Maguire do? When Brenda starts dating a new guy (Henry Simmons), Kenny has to try even harder.